หน้าแรกPrimeCap™ T7 RNA Polymerase (low dsRNA)
หน้าแรกPrimeCap™ T7 RNA Polymerase (low dsRNA)

PrimeCap™ T7 RNA Polymerase (low dsRNA)

Overview

  • Produce in-vitro transcribed RNA with very low dsRNA byproduct that is notably safer for in vivo administration
  • Retain the same high yields as T7 RNA polymerase ver.2 (Cat. # 2541A), especially when used with cap analogs such as CleanCap Reagent AG (TriLink Bio Technologies)
  • Get improved heat resistance (up to 52°C) compared to T7 RNA polymerase ver.2.0

 

Product Description

Trace amounts of double-stranded RNA (dsRNA) byproduct produced during in vitro transcription can interfere with downstream in vivo administration by triggering unwanted immune responses. PrimeCap T7 RNA Polymerase (low dsRNA) is a modified form of T7 RNA polymerase that combines highly efficient cap-analog-dependent RNA synthesis with extremely low dsRNA generation, making it the ideal choice for researchers engaged in mRNA therapeutic research and development.

 

Substance

PrimeCap T7 RNA Polymerase, HQ (200 U/μl)　　　200,000 U 10× IVT Reaction Buffer, HQ　　　10 ml

 

Preservation

－20℃

 

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