หน้าแรกRetroNectin® (Recombinant Human Fibronectin Fragment)
หน้าแรกRetroNectin® (Recombinant Human Fibronectin Fragment)

RetroNectin® (Recombinant Human Fibronectin Fragment)

Overview

  • Enhanced gene transfer efficiency for retroviral or lentiviral transduction of suspension cells, hematopoietic stem cells, and other hard-to-infect cell types
  • Less toxicity than other commonly used transduction enhancers, including polybrene and protamine
  • Fully recombinant peptide
  • The efficiency of T cell (CD8+) expansion can be significantly increased in the presence of RetroNectin reagent
  • RetroNectin GMP grade (Cat # T202), is manufactured and tested in accordance with the following guidelines, "Standards for Manufacturing Control and Quality Control, etc. of Investigational Products (Investigational products GMP)" notified by the Ministry of Health and Welfare Japan ("PFSB Notification No. 0709002, July 9, 2008)" (PFSB: Pharmaceutical and Food Safety Bureau)

 

Product Description

Research using hematopoietic cells and other suspension cells has been limited in part by low efficiency of gene transfer (transduction and transfection) into these cell types. RetroNectin reagent promotes colocalization of lentivirus or retrovirus with target cells to dramatically enhance transduction efficiency. As a consequence, RetroNectin reagent is now the gold standard transduction enhancer for retroviral/lentiviral gene transfer to hematopoietic cells and holds great promise in clinical application, having been used for over 40 clinical trials.

 

Substance

RetroNectin 0.5 mg (0.5 ml) (Product Code T100A) RetroNectin 2.5 mg (2.5 ml) (Product Code T100B) This product is a solution (filtered and sterilized) (1 mg/ml). (shape) 12.5 mM sodium citrate (pH 6.2), 1.25% sucrose (Sucrose)

 

Preservation

Product codes: T100A, T100B －20℃ | Product code: T110A 4℃

 

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